GraphWise

The GraphWise project is an ongoing effort to design and develop an innovative new search engine. GraphWise can comb a network for data stored in tables, then index and normalize that data to produce a searchable database of graphs. GraphWise can extract tables from spreadsheets and other office documents, XML files, web pages and -- to a limited extent -- PDF files. Proprietary algorithms (several patents pending) are used to "slice and dice" the extracted data to automatically generate graphs, charts and maps. The search results are presented graphically.

One key search capability unique to GraphWise is the ability to search for graphs by shape. The system indexes graphs by correlation of data across similar axes.

Currently, GraphWise is being developed as an enterprise appliance, for application to organizational intranets and virtual private networks.

StudyPharm

StudyPharm is a clinical trial management system, supported by IVR (interactive voice/response), web, fax and pager components. This project proves the effectiveness of Open Source systems. It was developed in PHP using highly distributed Postgres databases, Sphinx speech recognition (from CMU), the Apache web server, running on multiple Linux servers.

The StudyPharm application suite provides IVR for patient diaries and double-blind medication dispensing. The system manages trial medicine/device inventories, predicting and ordering supplies as needed based on complex treatment regimes.

Our clients for StudyPharm included the Harvard Clinical Research Institute, The Covalent Group(now Encorium), eTrials Worldwide (now Merge Healthcare), Antean, and Devon Health Services.

StudyPharm is highly flexible and scalable, since each study runs discretely on its own server with a dedicated bank of voice modems. The hardware cost for each study is minimal, with servers costing as little as $300 and modems under $100. Studies are able to be hosted for $20K to $30K, rather than the $100K to $300K cost that is more typical of the industry.

Due to its cost effectiveness and flexible design, Authentrics (known as ReQuest Technologies at the time) was able to design and host studies quickly and inexpensively for its CRO and pharmaceutical customers. This led to the acquisition of the system by eTrials Worldwide (itself recently acquired by Merge Healthcare). StudyPharm is in active use today under a different product name, servicing numerous trials with thousands of patients and clinicians around the globe.

Various Web Sites

Although web site design has not been our traditional specialty area, Authentrics has assisted with the development and deployment of some web sites.

Recently, a couple of graphic designers have been added to the Authentrics team. We hope to be doing more in this area in the future.

SBIR Research Project: "A Ubiquitous Multi-media Real-time Patient Diary System"

Under this effort we explored a client/server based system that would support data collection from a variety of sources, including wireless devices (via WML), cell phones, web browsers, and telephone IVR. The study produced a prototype application demonstrating the feasibility of our approach.

TeleTrial

The TeleTrial system was developed for a CRO customer, the Covalent Group (recently changed to "Encorium"). TeleTrial was a suite of applications that supported both patient information systems and some clinical trial management functionality. For our customer. we developed a number of systems for educating patients with chronic health issues, such as GERD or smoking addiction. The system evolved over time to assist the customer with their core business of managing clinical trials.

TeleTrial operated on a distributed, heterougenous network, including Unix data and telephony servers and MS Windows fax servers. The system relied largely on proprietary software, including SCO Unix, Oracle Databases, commercial speech recognition software, digital telephony boards and fax server applications.

TeleTrial managed systems for a wide range of pharmaceutical customers, including Pfizer, Merck, Schering-Plough (now part of Merck), Astra Zeneca, Wyeth (now part of Pfizer) and others.

CoLab

In its inception as ReQuest Technologies, Authentrics won a Small Business Innovative Research (SBIR) grant to develop a collaborative medical records application. Written using Oracle and OracleObjects, CoLab was a multimedia electronic medical record (EMR) system for use in obstetrics and gynecology clinics and hospital departments. The project was a feasibility study only, and produced a prototype application.